RECURRENT BRAIN TUMOR
\ɹɪkˈʌɹənt bɹˈe͡ɪn tjˈuːmə], \ɹɪkˈʌɹənt bɹˈeɪn tjˈuːmə], \ɹ_ɪ_k_ˈʌ_ɹ_ə_n_t b_ɹ_ˈeɪ_n t_j_ˈuː_m_ə]\
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Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.