SEITELBERGER DISEASE
\sˈe͡ɪtɪlbˌɜːɡə dɪzˈiːz], \sˈeɪtɪlbˌɜːɡə dɪzˈiːz], \s_ˈeɪ_t_ɪ_l_b_ˌɜː_ɡ_ə d_ɪ_z_ˈiː_z]\
Sort: Oldest first
-
A nonspecific term referring both to the pathologic finding of swelling of distal portions of axons in the brain and to disorders which feature this finding. Neuroaxonal dystrophy is seen in various genetic diseases, vitamin deficiencies, and aging. Infantile neuroaxonal dystrophy is an autosomal recessive disease characterized by arrested psychomotor development at 6 months to 2 years of age, ataxia, brain stem dysfunction, and quadriparesis. Juvenile and adult forms also occur. Pathologic findings include brain atrophy and widespread accumulation of axonal spheroids throughout the neuroaxis, peripheral nerves, and dental pulp. (From Davis & Robertson, Textbook of Neuropathology, 2nd ed, p927)
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- seismosaurus
- seismoscope
- seismotherapy
- seison
- seisura
- Seitelberger Disease
- seitelbergers disease
- seity
- seiurus
- seiurus aurocapillus
- seiz