NONDEPOLARIZING BLOCKERS
\nˌɒndiːpˈə͡ʊləɹˌa͡ɪzɪŋ blˈɒkəz], \nˌɒndiːpˈəʊləɹˌaɪzɪŋ blˈɒkəz], \n_ˌɒ_n_d_iː_p_ˈəʊ_l_ə_ɹ_ˌaɪ_z_ɪ_ŋ b_l_ˈɒ_k_ə_z]\
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Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.