MEASLES INCLUSION BODY ENCEPHALITIS
\mˈiːsə͡lz ɪnklˈuːʒən bˈɒdi ɛnsˌɛfɐlˈa͡ɪtɪs], \mˈiːsəlz ɪnklˈuːʒən bˈɒdi ɛnsˌɛfɐlˈaɪtɪs], \m_ˈiː_s_əl_z ɪ_n_k_l_ˈuː_ʒ_ə_n b_ˈɒ_d_i_ ɛ_n_s_ˌɛ_f_ɐ_l_ˈaɪ_t_ɪ_s]\
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A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)
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Nearby Words
- measle
- measle worm
- measled
- measles
- measles fusion protein
- Measles Inclusion Body Encephalitis
- measles mumps rubella vaccine
- measles vaccine
- measles virus
- measls
- measly