SEROTYPE B MENINGOCOCCAL MENINGITIS
\sˈɛɹətˌa͡ɪp bˈiː mˈɛnɪŋɡˌɒkɒkə͡l mˌɛnɪnd͡ʒˈa͡ɪtɪs], \sˈɛɹətˌaɪp bˈiː mˈɛnɪŋɡˌɒkɒkəl mˌɛnɪndʒˈaɪtɪs], \s_ˈɛ_ɹ_ə_t_ˌaɪ_p b_ˈiː m_ˈɛ_n_ɪ_ŋ_ɡ_ˌɒ_k_ɒ_k_əl m_ˌɛ_n_ɪ_n_dʒ_ˈaɪ_t_ɪ_s]\
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A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Neisseria meningitidis serogroups A, B, and C have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10 (1):13-8)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.