SEROTONIN UPTAKE INHIBITORS
\sˌɛɹətˈə͡ʊnɪn ˈʌpte͡ɪk ɪnhˈɪbɪtəz], \sˌɛɹətˈəʊnɪn ˈʌpteɪk ɪnhˈɪbɪtəz], \s_ˌɛ_ɹ_ə_t_ˈəʊ_n_ɪ_n ˈʌ_p_t_eɪ_k ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\
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Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.