GUIDO CAVALCANTI

\ɡwˈiːdə͡ʊ kˈavɐlkˌanti], \ɡwˈiːdə‍ʊ kˈavɐlkˌanti], \ɡ_w_ˈiː_d_əʊ k_ˈa_v_ɐ_l_k_ˌa_n_t_i]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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