GUIDING SYMPTOM
\ɡˈa͡ɪdɪŋ sˈɪmptəm], \ɡˈaɪdɪŋ sˈɪmptəm], \ɡ_ˈaɪ_d_ɪ_ŋ s_ˈɪ_m_p_t_ə_m]\
Definitions of GUIDING SYMPTOM
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.