GUIDO BENTIVOGLIO

\ɡwˈiːdə͡ʊ bˌɛntɪvˈɒɡlɪˌə͡ʊ], \ɡwˈiːdə‍ʊ bˌɛntɪvˈɒɡlɪˌə‍ʊ], \ɡ_w_ˈiː_d_əʊ b_ˌɛ_n_t_ɪ_v_ˈɒ_ɡ_l_ɪ__ˌəʊ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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