THIETHYLPERAZINE MALATE
\θˈa͡ɪ͡əθɪlpəɹˌe͡ɪziːn mˈale͡ɪt], \θˈaɪəθɪlpəɹˌeɪziːn mˈaleɪt], \θ_ˈaɪə_θ_ɪ_l_p_ə_ɹ_ˌeɪ_z_iː_n m_ˈa_l_eɪ_t]\
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A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.