SIMIAN VIRUS 40 VIRION PROTEIN 1
\sˈɪmi͡ən vˈa͡ɪɹəs fˈɔːti vˈɪɹi͡ən pɹˈə͡ʊtiːn wˈɒn], \sˈɪmiən vˈaɪɹəs fˈɔːti vˈɪɹiən pɹˈəʊtiːn wˈɒn], \s_ˈɪ_m_iə_n v_ˈaɪ_ɹ_ə_s f_ˈɔː_t_i v_ˈɪ_ɹ_iə_n p_ɹ_ˈəʊ_t_iː_n w_ˈɒ_n]\
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Viral proteins that do not regulate transcription. They are coded by viral structural genes and include nucleocapsid core proteins (gag proteins), enzymes (pol proteins), and membrane components (env proteins). Transcription of viral structural genes is regulated by viral regulatory proteins.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.