REINHOLD PAULI

\ɹˈa͡ɪnhə͡ʊld pˈɔːli], \ɹˈa‍ɪnhə‍ʊld pˈɔːli], \ɹ_ˈaɪ_n_h_əʊ_l_d p_ˈɔː_l_i]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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