PACHYDERMATOCELES
\pˈat͡ʃa͡ɪdəmˌatə͡ʊsə͡lz], \pˈatʃaɪdəmˌatəʊsəlz], \p_ˈa_tʃ_aɪ_d_ə_m_ˌa_t_əʊ_s_əl_z]\
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A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestion of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131 (5):678-82)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.