MASSIVE OSTEOLYSIS
\mˈasɪv ˌɒstɪˈɒləsˌɪs], \mˈasɪv ˌɒstɪˈɒləsˌɪs], \m_ˈa_s_ɪ_v ˌɒ_s_t_ɪ__ˈɒ_l_ə_s_ˌɪ_s]\
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Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (Gorham disease), multicentric (Hajdu-Cheney syndrome, Winchester syndrome), or carpal/tarsal.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.