HETERODUPLEX DNA
\hˈɛtɹə͡ʊdjˌuːplɛks dˌiːˌɛnˈe͡ɪ], \hˈɛtɹəʊdjˌuːplɛks dˌiːˌɛnˈeɪ], \h_ˈɛ_t_ɹ_əʊ_d_j_ˌuː_p_l_ɛ_k_s d_ˌiː__ˌɛ_n_ˈeɪ]\
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Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
By DataStellar Co., Ltd
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