DEFECTIVE INTERFERING VIRUS
\dɪfˈɛktɪv ˌɪntəfˈi͡əɹɪŋ vˈa͡ɪɹəs], \dɪfˈɛktɪv ˌɪntəfˈiəɹɪŋ vˈaɪɹəs], \d_ɪ_f_ˈɛ_k_t_ɪ_v ˌɪ_n_t_ə_f_ˈiə_ɹ_ɪ_ŋ v_ˈaɪ_ɹ_ə_s]\
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Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.