ADOPTIVE CELLULAR IMMUNOTHERAPIES
\ɐdˈɒptɪv sˈɛljʊləɹ ɪmjˈuːnə͡ʊθˌɛɹəpɪz], \ɐdˈɒptɪv sˈɛljʊləɹ ɪmjˈuːnəʊθˌɛɹəpɪz], \ɐ_d_ˈɒ_p_t_ɪ_v s_ˈɛ_l_j_ʊ_l_ə_ɹ ɪ_m_j_ˈuː_n_əʊ_θ_ˌɛ_ɹ_ə_p_ɪ_z]\
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Form of adoptive transfer where cells with antitumor activity are transferred to the tumor-bearing host in order to mediate tumor regression. The lymphoid cells commonly used are lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL). This is usually considered a form of passive immunotherapy. (From DeVita, et al., Cancer, 1993, pp.305-7, 314)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.