ACE INHIBITORS
\ˌe͡ɪsˌiːˈiː ɪnhˈɪbɪtəz], \ˌeɪsˌiːˈiː ɪnhˈɪbɪtəz], \ˌeɪ_s_ˌiː__ˈiː_ ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\
Sort: Oldest first
-
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.