KOZHEVNIKOW SYNDROME, PROGRESSIVE VARIANT

\kˈɒʒɪvnˌɪka͡ʊ sˈɪndɹə͡ʊm], \kˈɒʒɪvnˌɪka‍ʊ sˈɪndɹə‍ʊm], \k_ˈɒ_ʒ_ɪ_v_n_ˌɪ_k_aʊ s_ˈɪ_n_d_ɹ_əʊ_m]\

Definitions of KOZHEVNIKOW SYNDROME, PROGRESSIVE VARIANT

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2010 - Medical Dictionary Database
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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