FOLIC ACID DEFICIENCIES
\fˈɒlɪk ˈasɪd dɪfˈɪʃənsɪz], \fˈɒlɪk ˈasɪd dɪfˈɪʃənsɪz], \f_ˈɒ_l_ɪ_k ˈa_s_ɪ_d d_ɪ_f_ˈɪ_ʃ_ə_n_s_ɪ_z]\
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A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
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