CLARA DOTY BATES

\klˈɑːɹə dˈə͡ʊti bˈe͡ɪts], \klˈɑːɹə dˈə‍ʊti bˈe‍ɪts], \k_l_ˈɑː_ɹ_ə d_ˈəʊ_t_i b_ˈeɪ_t_s]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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