SKIN AGING
\skˈɪn ˈe͡ɪd͡ʒɪŋ], \skˈɪn ˈeɪdʒɪŋ], \s_k_ˈɪ_n ˈeɪ_dʒ_ɪ_ŋ]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.