PROMOTORS (GENETICS)
\pɹəmˈə͡ʊtəz d͡ʒɛnˈɛtɪks], \pɹəmˈəʊtəz dʒɛnˈɛtɪks], \p_ɹ_ə_m_ˈəʊ_t_ə_z__ dʒ_ɛ_n_ˈɛ_t_ɪ_k_s]\
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DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.