NAHUM CAPEN

\nˈahəm kˈe͡ɪpən], \nˈahəm kˈe‍ɪpən], \n_ˈa_h_ə_m k_ˈeɪ_p_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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