MDR1 PROTEIN
\ˌɛmdˌiːˈɑː wˈɒn pɹˈə͡ʊtiːn], \ˌɛmdˌiːˈɑː wˈɒn pɹˈəʊtiːn], \ˌɛ_m_d_ˌiː__ˈɑː w_ˈɒ_n p_ɹ_ˈəʊ_t_iː_n]\
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A 170 kD transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
By DataStellar Co., Ltd
Word of the day
Snake's-head
- Guinea-hen flower; -- so called in England because its spotted petals resemble the scales of a snake's head.