LIUBEN KARAVELOV

\lˈɪjuːbən kˈaɹɐvˌɛlʌv], \lˈɪjuːbən kˈaɹɐvˌɛlʌv], \l_ˈɪ_j_uː_b_ə_n k_ˈa_ɹ_ɐ_v_ˌɛ_l_ʌ_v]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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