GIUSEPPE PARINI

\d͡ʒˈɪjuːsˌɛp pe͡əɹˈiːnɪ], \d‍ʒˈɪjuːsˌɛp pe‍əɹˈiːnɪ], \dʒ_ˈɪ_j_uː_s_ˌɛ_p p_eə_ɹ_ˈiː_n_ɪ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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