CASTELLETTO ADONO, WATERS OF

\kˌastɪlˈɛtə͡ʊ adˈə͡ʊnə͡ʊ], \kˌastɪlˈɛtə‍ʊ adˈə‍ʊnə‍ʊ], \k_ˌa_s_t_ɪ_l_ˈɛ_t_əʊ a_d_ˈəʊ_n_əʊ]\

Definitions of CASTELLETTO ADONO, WATERS OF

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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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