APPLETON RULE
\ˈapə͡ltən ɹˈuːl], \ˈapəltən ɹˈuːl], \ˈa_p_əl_t_ə_n ɹ_ˈuː_l]\
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.