RETROGRADE DEGENERATIONS
\ɹˌɛtɹə͡ʊɡɹˈe͡ɪd dɪd͡ʒˌɛnəɹˈe͡ɪʃənz], \ɹˌɛtɹəʊɡɹˈeɪd dɪdʒˌɛnəɹˈeɪʃənz], \ɹ_ˌɛ_t_ɹ_əʊ_ɡ_ɹ_ˈeɪ_d d_ɪ_dʒ_ˌɛ_n_ə_ɹ_ˈeɪ_ʃ_ə_n_z]\
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Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.