REPTILASE DEF
\ɹˈɛptɪlˌe͡ɪs dˌiːˌiːˈɛf], \ɹˈɛptɪlˌeɪs dˌiːˌiːˈɛf], \ɹ_ˈɛ_p_t_ɪ_l_ˌeɪ_s d_ˌiː__ˌiː__ˈɛ_f]\
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A proteolytic enzyme obtained from the venom of fer-de-lance (Bothrops atrox). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.