NEUTRALIZATION TEST
\njˌuːtɹəla͡ɪzˈe͡ɪʃən tˈɛst], \njˌuːtɹəlaɪzˈeɪʃən tˈɛst], \n_j_ˌuː_t_ɹ_ə_l_aɪ_z_ˈeɪ_ʃ_ə_n t_ˈɛ_s_t]\
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Titration of an antiserum by testing a series of dilutions of virus or immune serum to a given end-point, which is generally the dilution at which tissue cultures inoculated with the serum-virus mixtures demonstrate cytopathology (CPE) or the dilution at which 50% of test animals injected with serum-virus mixtures show infectivity (ID50) or die (LD50).
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.