NEUTRALISATION

\njˌuːtɹəla͡ɪzˈe͡ɪʃən], \njˌuːtɹəla‍ɪzˈe‍ɪʃən], \n_j_ˌuː_t_ɹ_ə_l_aɪ_z_ˈeɪ_ʃ_ə_n]\

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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