INSTRUMENTUM CHIRURGICUM
\ˌɪnstɹəmˈɛntəm kˈa͡ɪɹəd͡ʒˌɪkəm], \ˌɪnstɹəmˈɛntəm kˈaɪɹədʒˌɪkəm], \ˌɪ_n_s_t_ɹ_ə_m_ˈɛ_n_t_ə_m k_ˈaɪ_ɹ_ə_dʒ_ˌɪ_k_ə_m]\
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By Robley Dunglison
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.