DELINEATIVE
\dɪlˈɪni͡ətˌɪv], \dɪlˈɪniətˌɪv], \d_ɪ_l_ˈɪ_n_iə_t_ˌɪ_v]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.