CHAPUT'S METHOD
\t͡ʃˈapʊts mˈɛθəd], \tʃˈapʊts mˈɛθəd], \tʃ_ˈa_p_ʊ_t_s m_ˈɛ_θ_ə_d]\
Definitions of CHAPUT'S METHOD
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.