CHAPTREL
\t͡ʃˈaptɹə͡l], \tʃˈaptɹəl], \tʃ_ˈa_p_t_ɹ_əl]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.