SIGNORELLI'S SIGN

\sɪnjˈɔːliz sˈa͡ɪn], \sɪnjˈɔːliz sˈa‍ɪn], \s_ɪ_n_j_ˈɔː_l_i_z s_ˈaɪ_n]\

Definitions of SIGNORELLI'S SIGN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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