PATRIOTEER
\pˌatɹɪə͡ʊtˈi͡ə], \pˌatɹɪəʊtˈiə], \p_ˌa_t_ɹ_ɪ__əʊ_t_ˈiə]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.