MEN2A
\mˈɛn tˈuː ˈe͡ɪ], \mˈɛn tˈuː ˈeɪ], \m_ˈɛ_n t_ˈuː ˈeɪ]\
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A type of multiple endocrine neoplasia characterized by a virtually 100% incidence of medullary thyroid carcinoma, a 50% incidence of pheochromocytoma, and a lesser incidence of parathyroid adenomas associated with hyperparathyroidism. The condition is always transmitted through autosomal dominant inheritance. Genetic testing can identify individuals with the trait in early infancy. Treatment is usually excision of the enlarged parathyroid glands. (From Holland et al., Cancer Medicine, 3d ed, pp1172-75)
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].