HALSTED'S METHOD

\hˈalstɪdz mˈɛθəd], \hˈalstɪdz mˈɛθəd], \h_ˈa_l_s_t_ɪ_d_z m_ˈɛ_θ_ə_d]\

Definitions of HALSTED'S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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