GOLDSCHEIDER'S METHOD

\ɡˈə͡ʊldst͡ʃe͡ɪdəz mˈɛθəd], \ɡˈə‍ʊldst‍ʃe‍ɪdəz mˈɛθəd], \ɡ_ˈəʊ_l_d_s_tʃ_eɪ_d_ə_z m_ˈɛ_θ_ə_d]\

Definitions of GOLDSCHEIDER'S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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