DISSEMINATOR

\dɪsˈɛmɪnˌe͡ɪtə], \dɪsˈɛmɪnˌe‍ɪtə], \d_ɪ_s_ˈɛ_m_ɪ_n_ˌeɪ_t_ə]\
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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe
 
1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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