CIRCLE CHIRURGICUM
\sˈɜːkə͡l kˈa͡ɪɹəd͡ʒˌɪkəm], \sˈɜːkəl kˈaɪɹədʒˌɪkəm], \s_ˈɜː_k_əl k_ˈaɪ_ɹ_ə_dʒ_ˌɪ_k_ə_m]\
Definitions of CIRCLE CHIRURGICUM
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.