CAUSA CONJUNCTA

\kˈɔːsə kənd͡ʒˈʌŋktə], \kˈɔːsə kənd‍ʒˈʌŋktə], \k_ˈɔː_s_ə k_ə_n_dʒ_ˈʌ_ŋ_k_t_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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