TRK1 TRANSFORMING TRYROSINE KINASE
\tˌiːˌɑːkˈe͡ɪ wˈɒn tɹansfˈɔːmɪŋ tɹˈa͡ɪɹəsˌa͡ɪn kˈɪne͡ɪs], \tˌiːˌɑːkˈeɪ wˈɒn tɹansfˈɔːmɪŋ tɹˈaɪɹəsˌaɪn kˈɪneɪs], \t_ˌiː__ˌɑː_k_ˈeɪ w_ˈɒ_n t_ɹ_a_n_s_f_ˈɔː_m_ɪ_ŋ t_ɹ_ˈaɪ_ɹ_ə_s_ˌaɪ_n k_ˈɪ_n_eɪ_s]\
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A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with congenital insensitivity to pain with anhidrosis, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. EC 2.7.11.-.
By DataStellar Co., Ltd
Word of the day
basidiomycota
- comprises fungi bearing the spores on basidium: Gasteromycetes (puffballs); Tiliomycetes (comprising orders Ustilaginales (smuts) and Uredinales (rusts)); Hymenomycetes (mushrooms; toadstools; agarics; bracket fungi); in some classification systems considered a division of kingdom comprises fungi bearing spores on a basidium; includes Gasteromycetes (puffballs) Tiliomycetes comprising the orders Ustilaginales (smuts) and Uredinales (rusts) Hymenomycetes (mushrooms, toadstools, agarics bracket fungi).
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