SYMMETRICAL GANGRENE

\sɪmˈɛtɹɪkə͡l ɡˈaŋɡɹiːn], \sɪmˈɛtɹɪkə‍l ɡˈaŋɡɹiːn], \s_ɪ_m_ˈɛ_t_ɹ_ɪ_k_əl ɡ_ˈa_ŋ_ɡ_ɹ_iː_n]\

Definitions of SYMMETRICAL GANGRENE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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