STOPPER KNOT
\stˈɒpə nˈɒt], \stˈɒpə nˈɒt], \s_t_ˈɒ_p_ə n_ˈɒ_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.