PERIOCULAR DERMATITIDES
\pˌi͡əɹɪˈɒkjʊlə dˈɜːmɐtˌɪta͡ɪdz], \pˌiəɹɪˈɒkjʊlə dˈɜːmɐtˌɪtaɪdz], \p_ˌiə_ɹ_ɪ__ˈɒ_k_j_ʊ_l_ə d_ˈɜː_m_ɐ_t_ˌɪ_t_aɪ_d_z]\
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A papular eruption of unknown etiology that progresses to residual papular erythema and scaling usually confined to the area of the mouth, and almost exclusively occurring in young women. It may also be localized or extend to involve the eyelids and adjacent glabella area of the forehead (periocular dermatitis). (Dorland, 28th ed)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.