PARALYTIC APHONIA

\pˌaɹəlˈɪtɪk afˈə͡ʊni͡ə], \pˌaɹəlˈɪtɪk afˈə‍ʊni‍ə], \p_ˌa_ɹ_ə_l_ˈɪ_t_ɪ_k a_f_ˈəʊ_n_iə]\

Definitions of PARALYTIC APHONIA

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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